Find disease awareness content and relevant supporting materials

Read a transcript of Benedikt Schoser and Christoph Wanner exploring family planning in Fabry disease, supporting women in pregnancy and beyond.

A study of more than 3.3 million people found a rare inherited EGFR T790M mutation was associated with substantially higher lung cancer risk, particularly among never-smokers. Separately, a randomized trial found intrauterine mepivacaine reduced pain during intrauterine device insertion in women who had never given birth.

This Canadian Cardiovascular Society (CCS)/Canadian Heart Failure Society (CHFS) update supports a unified treatment approach for symptomatic heart failure with LVEF >40%, replacing the traditional separation of HFmrEF and HFpEF. Based on GRADE methodology and meta-analyses, the guideline outlines the role of SGLT2 inhibitors, MRAs, ARNIs and GLP-1 receptor agonists in reducing heart failure hospitalisation and optimising guideline-directed medical therapy.

The iCARDIO Alliance provides evidence-based recommendations for heart failure management that are intended to support implementation across diverse healthcare systems. The guideline integrates novel therapies, current standards of care and resource-adjusted treatment strategies to improve patient outcomes worldwide.

International clinical practice recommendations developed using GRADE methodology provide evidence-based guidance on the diagnosis and lifelong management of nephropathic cystinosis. The recommendations address early diagnosis, cysteamine therapy, renal and extra-renal complications, and multidisciplinary care in children and adults to support long-term outcomes.

Developed by the Cystic Fibrosis Foundation, these evidence-informed recommendations address the assessment, management and communication of pain in people living with cystic fibrosis. The guidance promotes a multimodal approach to pain care, with consideration of age, underlying causes of pain, health equity and quality-of-life outcomes.

These evidence-based recommendations from ASH address frontline management of acute lymphoblastic leukemia in adolescents and young adults. The guidance supports pediatric-inspired asparaginase-containing regimens, outlines the role of stem cell transplantation in higher-risk patients, and reviews emerging evidence for targeted therapies.

This guideline reviews recent advances in the diagnosis and management of primary mediastinal B-cell lymphoma, including PET-adapted treatment strategies and evolving systemic therapies. It provides practical guidance on radiotherapy decision-making, response assessment, and management following chemoimmunotherapy for healthcare professionals.

Find out more about the International Association for the Study of Lung Cancer World Conference on Lung Cancer and related resources for healthcare professionals.

Read a transcript of our interview with Giannis Mountzios, MD, PhD, on key advances in small-cell lung cancer (SCLC) from WCLC 2026.