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Navigating Multiple Myeloma

Multiple myeloma case studies

Last updated: 27th Mar 2026
Published: 27th Mar 2026

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Patient case: Treatment selection in RRMM

Step into a strategic match where each move counts. Follow a real-world patient case, guided by a multiple myeloma (MM) expert, and consider what your next move would be as you complete the quizzes on MM management and treatment selection in people with relapsed/refractory MM (RRMM).

Patient profile: Consider your tactics

Video of KOL or figure introducing patient could be used here

Elena Zamagni introduces Lorenzo, a 70-year-old patient who remains physically active and has relapsed/refractory multiple myeloma. Lorenzo has undergone one previous line of therapy. Join the discussion as we review his clinical journey and consider optimal next steps for treatment selection, guided by expert insights in MM management.

What move would you make?

Take the quiz

1. What 2L treatment would you choose for this patient?

Examine the data and re-evaluate the position

[Video from Elena Zamagni]

Elena Zamagni outlines her primary considerations in selecting an appropriate second-line therapy for this patient, referencing the latest EHA-ESMO recommendations and emphasizing essential clinical data that inform her choice of treatment.

What move would you make?

Take the quiz

1. What 2L treatment would you now choose for this patient?

Endgame: Patient outcomes

Endgame: Patient outcomes

Elena Zamagni details the next steps in Lorenzo’s treatment journey, sharing the latest information on his response to therapy. She also explains how considering potential third-line options influenced her approach to selecting the most appropriate second-line regimen.

View the EHA 2025 symposium highlights for expert insights on selecting treatment regimens in patients with newly diagnosed MM.

 

Meet the expert

A professional headshot of Elena Zamagni, MD, PhD Elena Zamagni, MD, PhD

Elena Zamagni is Associate Professor of Hematology at the University of Bologna, Italy. Her research interests include areas related to MM, in particular on the role of high-dose therapy with stem cell support, of prognostic factors, minimal residual disease, novel therapies, and of imaging techniques.

Disclosures: [Disclosures included here].

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